Multiple Sclerosis: A Personal Perspective

In the second STEAM class of my sophomore year, we are learning about the body. This class is called Disease, the first unit is called Body. In this unit, we learned mostly science. We learned about cancer and how that affects the body. We also learned about each organ system and the organs included in them and what they do. I am a total surgical junkie, so I already knew all of the material in this unit, I did break off a little bit and did some extra research for myself. We also learned a math concept called completing the square. This is another way to solve quadratic equations. I have done a lot of work in quadratics in the past, but I have never learned this technique. It was actually really easy to learn and same a lot of sense. We did not take any FEs this unit, but I hope for some cool ones in the following units. For this action project, we were asked to conduct an interview. It had to be anonymous but we had to find someone with a disease and interview them about it. We then had to write up their profile and classify their disease in accordance with what we learned in class. We also had to draw a picture of each of the body systems that the disease affects. I made the outline of a human body and then used transparencies to draw the affected organ systems. I interviewed a woman in her late 40s with Multiple Sclerosis. I really liked this project, I was able to talk about the things I love to learn about. I really didn't have any issues with this project and I look forward to the rest of this class and the next class.

For this action project, I thought about who I could interview. I have some family members and some friends who have or have had diseases. I decided to interview someone with Multiple Sclerosis.

Multiple Sclerosis

Multiple sclerosis or MS is an autoimmune disorder of the central nervous system or CNS. The CNS is the body’s control system. An autoimmune disease is when the body’s immune system attacks a healthy system or organ in the body. In the case of MS, the body’s immune system is attacking the myelin, which is the protective sheath on the nerve fibers, brain, and spinal cord. The myelin is damaged and interrupts the signals from the brain and the nerves, eventually leaving the nerves damaged. MS patients may have a wide variety of signs and symptoms depending on which nerves and how many nerves are affected. It could be a very small localized area or large areas. MS can have drastic effects on life. The loss of motor function or blindness are some extreme symptoms of MS. Some less severe cases can be managed with medication with little or no symptoms in day-to-day life. The most common type of MS disease course is a relapsing-remitting course. This means that symptoms of the disease come and go. Symptoms will appear over time and then get better. These periods of quiet time can last weeks to years. According to the Mayo Clinic, 60-70% or relapsing-remitting MS have steady progression and no relief time: this is called secondary progressive MS. There is also a course where people have a gradual onset and steady symptoms, this is called primary-progressive MS.

Symptoms

Symptoms of MS can vary from person to person. The most common type of symptoms a patient will experience are:

• Numbness and weakness in limbs
• Partial or total vision loss and pain when moving eyes
• Double vision
• Headaches
• Tingling in extremities
• Tremors
• Fatigue
• Dizziness
• Slurred speech.
• Problems with bladder and bowel function.

Classification

This disease is a genetic disease. MS is a non-transmittable disease. The cause of this disease is still unknown. The only way the disease is linked to other people is genetically. If you have a sibling or parent who had had MS, you are at higher risk of contracting the disease. MS is not transmitted through the air or bodily fluids. Some risk factors for contracting MS include:

• Family history - people with an immediate family member that has or had MS you are more at risk.
• Viruses - certain kinds of viruses have been connected with MS like the Epstein Barr virus that causes infectious mononucleosis. 
• Autoimmune diseases - diseases such as Type 1 diabetes, Thyroid disease, or Inflammatory Bowel Disease. Smoking also causes a higher risk of contracting MS. 
• Age - people between the ages of 15 and 60 are the most at risk for MS
• Gender - women are twice as likely of getting MS than men.

MS is most common in areas with temperate climates such as the northern US, Canada, south-eastern Australia, New Zealand, and Europe. The most common racial group to contract MS is people of Northern European descent. People who are of African, Asian, or Native-American descent have the lowest risk of contracting MS. There is no geo-economical link to MS at this point.

Nobody really knows why people contract MS but there are some risk factors like I stated before. The person I decided to interview is a 48-year-old female named Lynn. She has 2 teenage daughters and a husband. Lynn was diagnosed with MS 8 years ago in 2010. Lynn is a woman which means she was already at a higher risk. She also is of Northern European descent which it the most at risk racial group. She also lives and is from the northern United States which is one of the most at risk geographical locations. Lynn’s grandmother always had an undiagnosed neurological condition that could have been MS. Lynn also had Mononucleosis when she was in high school. This disease is caused by a bacteria that might be related to MS.

Lynn

It was the summer of 2010 and Lynn was living her life normally. She one day started to notice something funny with her vision. “It was weird,” she said. “Because for a couple days, I had been like feeling like something was weird with my vision. It was just, I couldn’t quite put my finger on what was going on, but it was like when I would turn my head quickly, my eyes weren't tracking right. We went to a dance recital and I really realized I was seeing double.” These are both very common symptoms of MS. Lynn also had a strange tingling feeling on her thigh. “It was like I had had a Novocaine shot.” she described. “ I did mention it to my doctor, and she said (“Well, I’m sure you don’t have MS.”)” It turns out the doctor was wrong. Lynn also experienced numbness and tingling on her extremities, another very common symptom. She was finally diagnosed later in the summer.

Lynn was diagnosed by the results of a series of tests. She underwent several MRIs which stands for Magnetic Resonance Imaging. These scanned her brain to look for lesions. She also underwent a Lumbar Puncture or Spinal Tap. This is a minor surgical procedure in which a large spinal needle is inserted between 2 lumbar vertebrae into the spinal canal to collect a sample of cerebrospinal fluid, this is the fluid that is on the outside of the spinal cord. The fluid is tested to rule out other neurological diseases such as meningitis.

Lynn’s treatment consisted mostly of medication and follow up imaging. MS is an incurable disease. Symptoms can be managed and pain can be relieved, but the disease is always going to be in the body. She was prescribed Copaxone which is a medication that blocks the immune system from attacking the brain or an Immunosuppressant. This medication must be taken daily and is administered by an injection beneath the skin. Lynn could give herself these injections at home. She would take this injection every night, she would rotate between her thigh, buttock, stomach, and arm.She recalled, “It was scary the first time I had to do it because I didn't know how it was going to feel. I was relieved that it was not as bad as I thought. I found that I had injection site reactions. Early on I had pancake sized welts that were red and itchy.” The side effects of this medication are bruising and skin irritation at the injection site.

When she was first diagnosed, Lynn was admitted to the hospital for a little over a week in the summer of 2010. This was because the intravenous steroids they were giving her called Solu Medrol needs constant blood testing and can damage the liver. “It was mostly annoying because I actually felt fine and didn’t feel like there was a reason I needed to be in the hospital. I was mostly worried about my kids because they were only 8 and 5.”

Today, Lynn lives life much like anyone else would. She has to take her Gilenya pill every night. She now takes this pill instead of the injection. Lynn’s symptoms are managed by the medication and she has no side effects in her day-to-day life. Lynn still has to go to frequent doctor’s appointments for MRI’s neuro exams and blood testing. These are all precautions to make sure she is prepared and aware if she has a relapse.

CM "Nervous System" (2018)

MS affects a few systems of the body. The main one is the Nervous system. The nervous system is bodies control system. The brain makes all of our decisions and our nerves make us move and feel pain. Our sensory organs pick up on external senses and turn that into information to our brain. The lymphatic system attacks the coating on the nerves and causes damage and can eventually destroy them. The coating on the nerves Myelin also coats the brain and spinal cord. This is the coating that deteriorates and leaves the nerves damaged.

CM. "Lymphatic System." (2018)

The Lymphatic System is the body’s defense system. It protects us from diseases. The Lymph nodes produce the chemical lymph that fight diseases. Sometimes the immune system attacks healthy parts of our bodies. This is called an Autoimmune disease. In a person with MS, the immune system attacks the healthy coating on the nerve fibers causing them to become damaged.

CM. "Digestive System." (2018)

The Digestive System is the body’s processing system. Food goes in and is processed and the waste comes out. The intestines absorb nutrients from the food and add water. They then empty the waste out the anus. In patients with MS, one symptom might be problems with bowel control. This means patents might have a hard time controlling when they defecate..

CM. "Renal System." (2018)

The Renal or Urinary System is the body’s liquid waste system. The kidneys filter the blood and absorb the nutrients. The waste from the filtered blood then goes down the Ureters into the Bladder, which is a holding place for the liquid waste. When the body has to urinate, the liquid is released into the urethra where it exits the body. Some patients with MS might have trouble with bladder function. This means patients may have a hard time controlling when they can urinate.

In conclusion, I really liked this project and didn't really have any trouble with it. The only problem was that I included too much information. I was over 400 words over the limit. I had to take out a lot of information that I thought was valuable, so I didn't like that much. Other than that, everything went smoothly and I am proud of how it came out.

Works Cited:

“Diagnosis.” (2017) Mayo Clinic. Mayo Foundation for Medical Education and Research. Web. 15, Feb, 2018.
https://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/diagnosis-treatment/drc-20350274

Moody, C. (2018, February 11) Personal Interview.

“Multiple Sclerosis.” (2017) Mayo Clinic. Mayo Foundation for Medical Education and Research. Web. 9, Feb, 2018.
https://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/symptoms-causes/syc-20350269

“What Causes MS?” (2018) National MS Society.org. National Multiple Sclerosis Society. Web. 9, Feb, 2018.
https://www.nationalmssociety.org/What-is-MS/What-Causes-MS